• Product NameBumetanide
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityBumetanide is a Loop Diuretic. The physiologic effect of bumetanide is by means of Increased Diuresis at Loop of Henle.
• Target NameNa-K-Cl cotransporter inhibitor
• CAS No. 28395-03-1
• Calculated MW 364.41
• Formulation C17H20N2O5S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CCCCNC1=C(OC2=CC=CC=C2)C(=CC(=C1)C(O)=O)S(N)(=O)=O
  Pathways:Membrane transporter/Ion channel
  Receptor:Na-K-Cl cotransporter
  Boling pt:
  Melting pt:230-231C
  Solubility:Ethanol: 36 mg/mL (98.78 mM); DMSO: 73 mg/mL (200.31 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Thakker RV. Adv Nephrol Necker Hosp. 1999;29:289-98.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting