• Product NameTrichlormethiazide
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityTrichlormethiazide is a thiazide diuretic with properties similar to those of hydrochlorothiazide. It is usually administered for the treatment of oedema (including that which is associated with heart failure, hepatic cirrhosis and corticosteroid therapy) and hypertension.
• Target NameATPase inhibitor; Carbonic Anhydrase inhibitor
• CAS No. 133-67-5
• Calculated MW 380.66
• Formulation C8H8Cl3N3O4S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C(Cl)Cl
  Pathways:Membrane transporter/Ion channel; Metabolism
  Receptor:Na+/K+-ATPase; Carbonic anhydrase
  Boling pt:631.3C
  Melting pt:248-250C
  Solubility:DMSO: 54 mg/mL (141.85 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Temperini C, et al. Bioorg Med Chem. 2009 Feb 1;17(3):1214-21.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting