• Product NameVigabatrin
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityAn analogue of gamma-aminobutyric acid, vigabatrin is an irreversible inhibitor of 4-aminobutyrate transaminase, the enzyme responsible for the catabolism of gamma-aminobutyric acid. (From Martindale The Extra Pharmacopoeia, 31st ed). Off-label uses include treatment of cocaine dependence.
• Target NameABC antagonist; GABA Receptor agonist
• CAS No. 60643-86-9
• Calculated MW 129.16
• Formulation C6H11NO2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:NC(CCC(O)=O)C=C
  Pathways:Membrane transporter/Ion channel; Neuroscience
  Receptor:ABAT; GABA
  Boling pt:73C
  Melting pt:209C
  Solubility:Water: 55.1 mg/mL
  Appearance:Gray Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Tyacke RJ, et al. Adv Pharmacol. 2010;58:373-96.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting