• Product NameMirtazapine
• Brief DescriptionInhibitors
• Purification99.71%
• Biological ActivityMirtazapine is an antidepressant introduced by Organon International in 1996 used for the treatment of moderate to severe depression. Mirtazapine has a tetracyclic chemical structure and is classified as a noradrenergic and specific serotonergic antidepressant (NaSSA). It is the only tetracyclic antidepressant that has been approved by the Food and Drug Administration to treat depression.
• Target Name5-HT Receptor antagonist; Adrenergic Receptor antagonist; Dopamine Receptor antagonist; Opioid Receptor agonist
• CAS No. 85650-52-8
• Calculated MW 265.35
• Formulation C17H19N3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CN1CCN2C(C1)C1=CC=CC=C1CC1=C2N=CC=C1
  Pathways:Endocrinology/Hormones; Neuroscience; GPCR/G Protein
  Receptor:5-HT; HT; Sert (Sodium-dependent); Adrenergic Receptor; DA transporter; Dopamine; κ-opioid receptor
  Boling pt:432.4C
  Melting pt:114-116C
  Solubility:Ethanol: 53 mg/mL (199.73 mM); DMSO: 53 mg/mL (199.73 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Laakmann G, et al. Psychoneuroendocrinology. 1999 Oct; 24(7):769-84.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting