• Product NameNebivolol hydrochloride
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityNebivolol hydrochloride selectively inhibits?β1- adrenergic receptor with?IC50?of 0.8 nM.
• Target NameAdrenergic Receptor antagonist
• CAS No. 152520-56-4
• Calculated MW 441.9
• Formulation C22H25F2NO4HCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:Cl.OC(CNCC(O)C1CCC2=C(O1)C=CC(F)=C2)C1CCC2=C(O1)C=CC(F)=C2
  Pathways:GPCR/G Protein
  Receptor:β1-adrenoceptor
  Boling pt:600.5C
  Melting pt:220-222C
  Solubility:DMSO: 88 mg/mL (199.14 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Pauwels PJ, et al. Mol Pharmacol, 1988, 34(6), 843-851.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting