• Product NameMitoxantrone hydrochloride
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityMitoxantrone Dihydrochloride, a type II topoisomerase inhibitor, is an anthracenedione-derived antineoplastic agent.
• Target NameTopoisomerase inhibitor
• CAS No. 70476-82-3
• Calculated MW 517.4
• Formulation C22H30Cl2N4O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:Cl.Cl.OCCNCCNC1=C2C(=O)C3=C(O)C=CC(O)=C3C(=O)C2=C(NCCNCCO)C=C1
  Pathways:DNA Damage/DNA Repair
  Receptor:Topo II
  Boling pt:805.7C
  Melting pt:203-205C
  Solubility:Water: 89 mg/mL (172.01 mM); DMSO: 89 mg/mL (172.01 mM)
  Appearance:Dark Purple Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Seitz M. Curr Opin Rheumatol, 1999, 11(3), 226-232.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting