• Product NameFluticasone propionate
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityFluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis.
• Target NameEstrogen/progestogen Receptor agonist; Glucocorticoid Receptor agonist; GR inhibitor; Phospholipase inhibitor
• CAS No. 80474-14-2
• Calculated MW 500.57
• Formulation C25H31F3O5S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:CCC(=O)O[C@@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)C)C(=O)SCF
  Pathways:Endocrinology/Hormones; Metabolism
  Receptor:ER; Mineralocorticoid Receptor; Glucocorticoid Receptor; Cytosolic PLA2
  Boling pt:568.3C
  Melting pt:275C
  Solubility:Ethanol: 5 mg/mL (9.98 mM); DMSO: 100 mg/mL (199.77 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Andersson O, et al. J Allergy Clin Immunol. 1999 Apr;103(4):595-600.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting