- Product NameSitagliptin
- Brief DescriptionInhibitors
- Purification98.00%
- Biological ActivitySitagliptin is a new oral hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. This enzyme-inhibiting drug is to be used either alone or in combination with metformin or a thiazolidinedione for control of type 2 diabetes mellitus. The drug works to competitively inhibit a protein/enzyme, dipeptidyl peptidase 4 (DPP-4), that results in an increased amount of active incretins (GLP-1 and GIP), reduced amount of release of glucagon (diminishes its release) and increased release of insulin.
- Target NameDPP-4 inhibitor
- CAS No. 486460-32-6
- Calculated MW 407.32
- Formulation C16H15F6N5O
- Storage 3 years -20˚C powder;2 years -80˚C in solvent;
