• Product NameClomipramine hydrochloride
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityClomipramine HCl is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively.
• Target Name5-HT Receptor antagonist; GST inhibitor; Norepinephrine inhibitor
• CAS No. 17321-77-6
• Calculated MW 351.31
• Formulation C19H23ClN2HCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:Cl.CN(C)CCCN1C2=CC=CC=C2CCC2=C1C=C(Cl)C=C2
  Pathways:GPCR/G Protein; Neuroscience; oxidation-reduction
  Receptor:5-HT; Sert (Sodium-dependent); GSTP; Noradrenaline transporter (Sodium-dependent)
  Boling pt:
  Melting pt:189-190C
  Solubility:Ethanol: 70 mg/mL (199.25 mM); Water: 70 mg/mL (199.25 mM); DMSO: 70 mg/mL (199.25 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Hastak K, et al. Y Res. 2010 Aug 26.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting