• Product NameAmcinonide
• Brief DescriptionInhibitors
• Purification99.49%
• Biological ActivityAmcinonide inhibit NO release from activated microglia with IC50 3.38 nM. Amcinonide has affinity for the glucocorticoid receptor.
• Target NameAnnexin A antagonist; GR antagonist
• CAS No. 51022-69-6
• Calculated MW 502.57
• Formulation C28H35FO7
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:CC(=O)OCC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@]4([C@H]3CCC5=CC(=O)C=C[C@@]54C)F)O)C)OC6(O2)CCCC6
  Pathways:GPCR/G Protein; Metabolism
  Receptor:Annexin A1; Glucocorticoid Receptor
  Boling pt:635.9C
  Melting pt:
  Solubility:DMSO: 10 mM
  Appearance:White Crystal
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Grossman R, et al. Ann N Y Acad Sci. 2006 Jul;1071:410-21.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting