• Product NameQuinidine hydrochloride
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityAn optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular action potential, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
• Target NamePotassium Channel inhibitor; Sodium Channel inhibitor
• CAS No. 6151-40-2
• Calculated MW 378.89
• Formulation C20H27ClN2O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:COC1=CC2=C(C=CN=C2C=C1)[C@@H]([C@H]3C[C@@H]4CCN3C[C@@H]4C=C)O.O.Cl
  Pathways:Membrane transporter/Ion channel
  Receptor:Potassium Channel; Sodium Channel
  Boling pt:495.9C?
  Melting pt:258-259C
  Solubility:DMSO: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Stokoe KS, et al. J Physiol. 2007 Jan 1;578(Pt 1):69-84.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting