• Product NameEvans blue
• Brief DescriptionInhibitors
• Purification98.85%
• Biological ActivityEvans Blue is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Able to antagonize AMPA and kainate receptor mediated currents (IC50 values are 220 and 150 nM, respectively).
• Target NameGluR inhibitor
• CAS No. 314-13-6
• Calculated MW 960.78
• Formulation C34H24N6Na4O14S4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N/N=C\3/C(=O)C4=C(C(=CC(=C4N)S(=O)(=O)[O-])S(=O)(=O)[O-])C=C3)C)N/N=C\5/C(=O)C6=C(C(=CC(=C6N)S(=O)(=O)[O-])S(=O)(=O)[O-])C=C5.[Na+].[Na+].[Na+].[Na+]
  Pathways:Neuroscience
  Receptor:vesicular glutamate uptake
  Boling pt:
  Melting pt:
  Solubility:Water: 10 mM
  Appearance:Black Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Shen Y, et al. Biomed Mater Eng. 2014;24(6):2831-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting