• Product NameDiphenhydramine hydrochloride
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityDiphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations.
• Target NameHistamine Receptor antagonist
• CAS No. 147-24-0
• Calculated MW 291.82
• Formulation C17H22ClNO
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:Cl.CN(C)CCOC(C1=CC=CC=C1)C1=CC=CC=C1
  Pathways:GPCR/G Protein; Immunology/Inflammation; Neuroscience
  Receptor:H1 receptor
  Boling pt:343.7C
  Melting pt:168-172C
  Solubility:Ethanol: 58 mg/mL (198.75 mM); Water: 58 mg/mL (198.75 mM); DMSO: 58 mg/mL (198.75 mM)
  Appearance:White Crystal
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Piao H, et al. Vascul Pharmacol. 2007 Apr;46(4):260-70.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting