• Product NameMinaprine dihydrochloride
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityMinaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain.
• Target Name5-HT Receptor antagonist; AChR inhibitor; Dopamine Receptor agonist; MAO inhibitor
• CAS No. 25905-77-5
• Calculated MW 371.3
• Formulation C17H22N4O2HCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:[H+].[H+].[Cl-].[Cl-].CC1=CC(=NN=C1NCCN1CCOCC1)C1=CC=CC=C1
  Pathways:GPCR/G Protein; Metabolism; Neuroscience
  Receptor:5-HT; Sert (Sodium-dependent); AChE; mAChR; Dopamine; MAO-A
  Boling pt:531.2C
  Melting pt:
  Solubility:soluble in Water
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kodama K, et al. Jpn J Pharmacol. 1992 Sep; 60(1):33-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting