• Product NameFenspiride hydrochloride
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityFenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases. It is approved for use in Russia for the treatment of acute and chronic inflammatory diseases of ENT organs and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis), as well as for maintenance treatment of asthma.
• Target NamePDE inhibitor
• CAS No. 5053-8-7
• Calculated MW 296.79
• Formulation C15H20N2O2HCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:C1CN(CCC12CNC(=O)O2)CCC3=CC=CC=C3.Cl
  Pathways:Metabolism
  Receptor:PDE3; PDE4
  Boling pt:474.3C
  Melting pt:235-238C
  Solubility:Water: 59 mg/mL (198.79 mM); DMSO: 9 mg/mL (30.32 mM)
  Appearance:White Crystal
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Cortijo J, et al. Eur J Pharmacol, 1998, 341(1), 79-86.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting