• Product NameCilnidipine
• Brief DescriptionInhibitors
• Purification99.83%
• Biological ActivityCilnidipine(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity.
• Target NameCalcium Channel inhibitor
• CAS No. 132203-70-4
• Calculated MW 492.53
• Formulation C27H28N2O7
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CC1=C(C(C(=C(N1)C)C(=O)OC/C=C/C2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OCCOC
  Pathways:Membrane transporter/Ion channel
  Receptor:Dual L-and N-type calcium channel
  Boling pt:
  Melting pt:97-99C
  Solubility:Ethanol: 15 mg/mL (30.45 mM); DMSO: 99 mg/mL (201.0 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Takahara A, et al. Hypertens Res,2003, 26(9), 743-747.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting