• Product NameAnastrozole
• Brief DescriptionInhibitors
• Purification99.73%
• Biological ActivityAnastrozole(ZD1033) is a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM) that has no discernible effect on adrenocorticoid hormone synthesis.
• Target NameAromatase inhibitor
• CAS No. 120511-73-1
• Calculated MW 293.37
• Formulation C17H19N5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:CC(C)(C#N)C1=CC(=CC(CN2C=NC=N2)=C1)C(C)(C)C#N
  Pathways:Endocrinology/Hormones
  Receptor:Aromatase
  Boling pt:469.7C
  Melting pt:81-82C
  Solubility:Ethanol: 59 mg/mL (201.11 mM); DMSO: 59 mg/mL (201.11 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Dukes M, et al. J Steroid Biochem Mol Biol, 1996, 58(4), 439-445.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting