• Product NameOxcarbazepine
• Brief DescriptionInhibitors
• Purification98%+
• Biological ActivityOxcarbazepine is structurally a derivative of carbamazepine, adding an extra oxygen atom to the benzylcarboxamide group. This difference helps reduce the impact on the liver of metabolizing the drug, and also prevents the serious forms of anemia occasionally associated with carbamazepine. Aside from this reduction in side effects, it is thought to have the same mechanism as carbamazepine - sodium channel inhibition - and is generally used to treat partial seizures in epileptic children and adults.
• Target NameSodium Channel inhibitor
• CAS No. 28721-07-5
• Calculated MW 252.27
• Formulation C15H12N2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:NC(=O)N1C2=CC=CC=C2CC(=O)C2=CC=CC=C12
  Pathways:Membrane transporter/Ion channel
  Receptor:Sodium Channel
  Boling pt:457C
  Melting pt:215-216C
  Solubility:DMSO: 7 mg/mL (27.74 mM)
  Appearance:Faint Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Vohora D, et al. Drugs Today (Barc). 2010 Apr; 46(4):265-77.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting