• Product NamePromethazine hydrochloride
• Brief DescriptionInhibitors
• Purification95.36%
• Biological ActivityPromethazine Hcl(NSC-231688) is the first-generation antihistamine; strong antagonist of the H1 receptor and moderate mACh receptor antagonist, moderate affinity for 5-HT2A, 5-HT2C, D2 and α1-adrenergic receptors.
• Target NameAdrenergic Receptor antagonist; Histamine Receptor antagonist
• CAS No. 58-33-3
• Calculated MW 320.88
• Formulation C17H20N2SHCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:Cl.CC(CN1C2=CC=CC=C2SC2=CC=CC=C12)N(C)C
  Pathways:GPCR/G Protein; Immunology/Inflammation; Neuroscience
  Receptor:α-adrenergic receptor; H1 receptor
  Boling pt:403.7C
  Melting pt:230-232C
  Solubility:Ethanol: 34 mg/mL (105.95 mM); Water: 64 mg/mL (199.45 mM); DMSO: 64 mg/mL (199.45 mM)
  Appearance:White or Gray Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Smith BN, Armstrong WE. Neuroscience. 1993 Apr;53(3):855-64.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting