• Product NameProbenecid
• Brief DescriptionInhibitors
• Purification99.95%
• Biological ActivityThe prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
• Target NameTRP/TRPV Channel inhibitor
• CAS No. 57-66-9
• Calculated MW 285.36
• Formulation C13H19NO4S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(O)=O
  Pathways:Membrane transporter/Ion channel
  Receptor:TRPV2
  Boling pt:
  Melting pt:194-196C
  Solubility:Ethanol: 22 mg/mL (77.09 mM); DMSO: 57 mg/mL (199.74 mM)
  Appearance:White Crystal
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. McDonough PM, et al. Cell Calcium, 1989, 10(3), 171-180.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting