• Product NameCilostazol
• Brief DescriptionInhibitors
• Purification99.86%
• Biological ActivityCilostazol is a medication used in the alleviation of the symptom of intermittent claudication in individuals with peripheral vascular disease. It is manufactured by Otsuka Pharmaceutical Co. under the trade name Pletal. Although drugs similar to cilostazol have increased the risk of death in patients with congestive heart failure, studies of significant size have not addressed people without the disease.
• Target NamePDE inhibitor
• CAS No. 73963-72-1
• Calculated MW 369.46
• Formulation C20H27N5O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:O=C1CCC2=C(N1)C=CC(OCCCCC1=NN=NN1C1CCCCC1)=C2
  Pathways:Metabolism
  Receptor:PDE3
  Boling pt:664.7C?
  Melting pt:159-160C
  Solubility:Ethanol: 6 mg/mL (16.23 mM); DMSO: 74 mg/mL (200.29 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Rondina MT, Weyrich AS. Handb Exp Pharmacol 2012(210):225-238.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting