• Product NameXylocaine
• Brief DescriptionInhibitors
• Purification99.74%
• Biological ActivityLidocaine, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (ICAM-1), and reduction of neutrophils influx.
• Target NameHistamine Receptor agonist
• CAS No. 137-58-6
• Calculated MW 234.34
• Formulation C14H22N2O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CCN(CC)CC(=O)NC1=C(C)C=CC=C1C
  Pathways:GPCR/G Protein; Immunology/Inflammation; Neuroscience
  Receptor:H1 receptor
  Boling pt:
  Melting pt:66-69C
  Solubility:Ethanol: 47 mg/mL (200.56 mM); Water: 9 mg/mL (38.4 mM); DMSO: 47 mg/mL (200.56 mM)
  Appearance:White Crystal
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sheets PL, et al. J Physiol. 2007 Jun 15;581(Pt 3):1019-31.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting