• Product NameNefopam hydrochloride
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityNefopam hydrochloride is a centrally-acting but non-opioid analgesic drug by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline reuptake.
• Target NameSodium Channel inhibitor
• CAS No. 23327-57-3
• Calculated MW 289.8
• Formulation C17H20ClNO
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:Cl.CN1CCOC(C2=CC=CC=C2)C2=CC=CC=C2C1
  Pathways:Membrane transporter/Ion channel
  Receptor:Sodium Channel
  Boling pt:369.5C?
  Melting pt:
  Solubility:Water: 21 mg/mL (72.46 mM); DMSO: 1 mg/mL (3.45 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. M. S. Evans1, et al, lBr J Anaesth, 2008, 101(5), 610-617.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting