• Product NameTimolol Maleate
• Brief DescriptionInhibitors
• Purification98.00%
• Biological Activity(S)-Timolol maleate, is a potent non-selective β-adrenergic receptor antagonist (Ki values are 1.97 and 2.0 nM for β1 and β2 receptor subtypes respectively).
• Target NameAdrenergic Receptor antagonist
• CAS No. 26921-17-5
• Calculated MW 432.5
• Formulation C17H28N4O7S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CC(C)(C)NC[C@@H](COC1=NSN=C1N2CCOCC2)O.C(=C\C(=O)O)\C(=O)O
  Pathways:GPCR/G Protein
  Receptor:β1-adrenergic receptor; β2-adrenergic receptor
  Boling pt:704.6C?
  Melting pt:202-203C
  Solubility:Ethanol: 86 mg/mL (198.84 mM); DMSO: 86 mg/mL (198.84 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Hall RA, et al. Arch Int Pharmacodyn Ther, 1975, 213(2), 251-263.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting