• Product NameMethacycline hydrochloride
• Brief DescriptionInhibitors
• Purification99.02%
• Biological ActivityMethacycline hydrochloride is a tetracycline antibiotic, and also an inhibitor of epithelialCmesenchymal transition (EMT) with IC50 of roughly 5 μM, used to treat various infections.
• Target Nameribosome agonist
• CAS No. 3963-95-9
• Calculated MW 478.88
• Formulation C22H23ClN2O8
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CN(C)[C@H]1[C@@H]2[C@H]([C@@H]3C(=C)C4=C(C(=CC=C4)O)C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O.Cl
  Pathways:Microbiology&virology
  Receptor:16S ribosome; 30S ribosome
  Boling pt:
  Melting pt:205C
  Solubility:Water: 5 mg/mL (10.44 mM); DMSO: 3 mg/mL (6.26 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Xi Y, et al. Am J Respir Cell Mol Biol,?014, 50(1), 51-60.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting