• Product NameAmitriptyline hydrochloride
• Brief DescriptionInhibitors
• Purification99.87%
• Biological ActivityAmitriptyline Hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA).
• Target Name5-HT Receptor antagonist; Norepinephrine inhibitor; Sigma receptor inhibitor
• CAS No. 549-18-8
• Calculated MW 313.86
• Formulation C20H24ClN
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:Cl.CN(C)CCC=C1C2=CC=CC=C2CCC2=CC=CC=C12
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:5-HT; 5-HT2; 5-HT4; Norepinephrine receptor; σ1
  Boling pt:
  Melting pt:196-197C
  Solubility:Ethanol: 63 mg/mL (200.72 mM); Water: 15 mg/mL (47.79 mM); DMSO: 63 mg/mL (200.72 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Vaishnavi SN, et al. Biol Psychiatry. 2004 Feb 1;55(3):320-2.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting