• Product NameKetoconazole
• Brief DescriptionInhibitors
• Purification99.62%
• Biological ActivityKetoconazole is an imidazole anti-fungal agent, a CYP3A4 inhibitor.
• Target NameHydroxylase inhibitor; NADPH-oxidase inhibitor; P450 inhibitor
• CAS No. 65277-42-1
• Calculated MW 531.43
• Formulation C26H28Cl2N4O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OC[C@H]3CO[C@](O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
  Pathways:Immunology/Inflammation; Metabolism
  Receptor:12-hydroxylase; 17-hydroxylase; Steroid 21-hydroxylase; Testosterone 6 beta-hydroxylase; Cyclosporine oxidase; CYP24A1; CYP3A4
  Boling pt:
  Melting pt:146C
  Solubility:Ethanol: 7 mg/mL (13.17 mM); DMSO: 3 mg/mL (5.64 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Eil C. Horm Metab Res. 1992 Aug;24(8):367-70.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting