• Product NameOrlistat
• Brief DescriptionInhibitors
• Purification100.00%
• Biological ActivityOrlistat is a drug designed to treat obesity. Its primary function is preventing the absorption of fats from the human diet, thereby reducing caloric intake. Orlistat works by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Without this enzyme, triglycerides from the diet are prevented from being hydrolyzed into absorbable free fatty acids and are excreted undigested.
• Target NameFatty Acid Synthase inhibitor; Others inhibitor
• CAS No. 96829-58-2
• Calculated MW 495.73
• Formulation C29H53NO5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CCCCCCCCCCC[C@@H](C[C@H]1[C@@H](C(=O)O1)CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
  Pathways:Metabolism; Others
  Receptor:FAS; triacylglycerol lipase
  Boling pt:615.9C
  Melting pt:<50C
  Solubility:Ethanol: 99 mg/mL (199.7 mM); DMSO: 99 mg/mL (199.7 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Uusitupa M. Curr Opin Lipidol. 1999 Feb;10(1):3-7.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting