• Product NameNiflumic acid
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityNiflumic acid, a Ca2+-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
• Target NameCOX inhibitor; Monocarboxylate transporter inhibitor; Others inducer; Phospholipase inhibitor; UGT inhibitor
• CAS No. 4394-00-7
• Calculated MW 282.22
• Formulation C13H9F3N2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:OC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)N=CC=C1
  Pathways:Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Others; Neuroscience
  Receptor:COX; Monocarboxylate transporter; Chloride channel protein ClC-Ka; PLA2; UGT
  Boling pt:
  Melting pt:203-204C
  Solubility:DMSO: 56 mg/mL (198.42 mM)
  Appearance:Off-white Color Crystal
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Jabeen T, et al. Acta Crystallogr D Biol Crystallogr. 2005 Dec;61(Pt 12):1579-86.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting