• Product NameNaftopidil
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityNaftopidil (INN, marketed under the brand name Flivas) is an antihypertensive drug which acts as a selective α1-adrenergic receptor antagonist or alpha blocker.
• Target NameAdrenergic Receptor antagonist
• CAS No. 57149-07-2
• Calculated MW 392.49
• Formulation C24H28N2O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:COC1=CC=CC=C1N1CCN(CC(O)COC2=CC=CC3=CC=CC=C23)CC1
  Pathways:GPCR/G Protein
  Receptor:α1A-adrenergic receptor; α1B-adrenergic receptor; α1D-adrenergic receptor
  Boling pt:
  Melting pt:127C
  Solubility:DMSO: 79 mg/mL (201.27 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sakai H, et al. Hinyokika Kiyo. 2011 Jan;57(1):7-13.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting