• Product NameCyclophosphamide monohydrate
• Brief DescriptionInhibitors
• Purification99.99%
• Biological ActivityPrecursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and Y.
• Target NameDNA Alkylation inducer; MRP inhibitor
• CAS No. 6055-19-2
• Calculated MW 279.1
• Formulation C7H17Cl2N2O2PH2O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:O.ClCCN(CCCl)P1(=O)NCCCO1
  Pathways:DNA Damage/DNA Repair; Immunology/Inflammation
  Receptor:DNA; MRP1
  Boling pt:336.1C
  Melting pt:49-51C
  Solubility:Water: 7 mg/mL (25.08 mM); DMSO: 55 mg/mL (197.06 mM)
  Appearance:White Crystal
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Ketolainen J, et al. Pharm Res. 1995 Feb;12(2):299-304.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting