• Product NameNiclosamide
• Brief DescriptionInhibitors
• Purification96.83%
• Biological ActivityNiclosamide(BAY2353) is used for the treatment of most tapeworm infections by inhibiting DNA replication.
• Target NameSTAT inhibitor
• CAS No. 50-65-7
• Calculated MW 327.12
• Formulation C13H8Cl2N2O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:OC1=C(C=C(Cl)C=C1)C(=O)NC1=C(Cl)C=C(C=C1)[N+]([O-])=O
  Pathways:JAK/STAT signaling; Stem Cells
  Receptor:STAT3
  Boling pt:424.5C
  Melting pt:225-230C
  Solubility:Ethanol: <1 mg/mL (<1 mM); Water: <1 mg/mL (<1 mM); DMSO: <1 mg/mL (<1 mM)
  Appearance:Gray Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Ren X, et al. ACS Med Chem Lett, 2010, 1(9), 454-459.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting