• Product NameDexchlorpheniramine Maleate
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityDexchlorpheniramine (trade name Polaramine) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically active dextrorotatory isomer of chlorpheniramine.
• Target Name5-HT Receptor inhibitor; Dopamine Receptor; Histamine Receptor antagonist; Norepinephrine inhibitor
• CAS No. 2438-32-6
• Calculated MW 390.86
• Formulation C20H23ClN2O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CN(C)CC[C@@H](C1=CC=C(C=C1)Cl)C2=CC=CC=N2.C(=C\C(=O)O)\C(=O)O
  Pathways:GPCR/G Protein; Neuroscience; Immunology/Inflammation
  Receptor:Sert (Sodium-dependent); DA transporter; H1 receptor; Noradrenaline transporter (Sodium-dependent)
  Boling pt:379C
  Melting pt:112-115C
  Solubility:Water: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Tagawa M, et al. Br J Clin Pharmacol. 2001 Nov;52(5):501-9.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting