• Product Name(-)-Sparteine sulfate pentahydrate
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivitySparteine is a class 1a antiarrhythmic agent; a sodium channel blocker. It is an alkaloid and can be extracted from scotch broom. It is the predominant alkaloid in Lupinus mutabilis, and is thought to chelate the bivalents calcium and magnesium. It is not FDA approved for human use as an antiarrhythmic agent, and it is not included in the Vaughn Williams classification of antiarrhythmic drugs.
• Target NameP450 inhibitor
• CAS No. 6160-12-9
• Calculated MW 422.54
• Formulation C15H38N2O9S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:C1CCN2C[C@@H]3C[C@H]([C@H]2C1)CN4[C@H]3CCCC4.O.O.O.O.O.OS(=O)(=O)O
  Pathways:Metabolism
  Receptor:CYP2D
  Boling pt:340.9C
  Melting pt:133-140C
  Solubility:Water: 0.1 g/mL
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Preissner S, et al. Nucleic Acids Res. 2010 Jan; 38(Database issue):D237-43.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting