• Product NameMethimazole
• Brief DescriptionInhibitors
• Purification99.94%
• Biological ActivityMethimazole(Tapazole, Northyx) is an antithyroid medicine. Target: Others Methimazole is an antithyroid drug, and part of the thioamide group. Like its counterpart propylthiouracil, a major side effect of treatment is agranulocytosis.
• Target NameThyroid hormone receptor(THR) inhibitor
• CAS No. 60-56-0
• Calculated MW 114.17
• Formulation C4H6N2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:CN1C=CNC1=S
  Pathways:Endocrinology/Hormones
  Receptor:Thyroid peripheral conversion
  Boling pt:280C
  Melting pt:144-147C
  Solubility:Ethanol: 23 mg/mL (201.45 mM); Water: 23 mg/mL (201.45 mM); DMSO: 23 mg/mL (201.45 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sugawara M, et al. Thyroid. 1999 May; 9(5):513-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting