• Product NameL-Thyroxine
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityL-Thyroxine(Levothyroxine) is an iodine containing hormone produced from thyroglobulin in the thyroid follicular cells; reduces total cholesterol level, low-density lipoprotein cholesterol as well as waist to hip ratio in subclinical hypothyroidism pateints.
• Target NameThyroid hormone receptor(THR) agonist
• CAS No. 51-48-9
• Calculated MW 776.87
• Formulation C15H11I4NO4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)C[C@@H](C(=O)O)N
  Pathways:Endocrinology/Hormones
  Receptor:Thyroid hormone
  Boling pt:
  Melting pt:235C
  Solubility:DMSO: 100 mg/mL (128.72 mM)
  Appearance:Off-white Color Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Marazuela M, et al. Thyroid. 2008 Oct; 18(10):1119-23.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting