• Product NameQuinacrine dihydrochloride
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityAn acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2..
• Target NameDNA Alkylation inhibitor; Histamine Receptor inhibitor; Phospholipase inhibitor
• CAS No. 1969-5-6
• Calculated MW 472.88
• Formulation C23H30CLN3O2HCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:[H+].[H+].[Cl-].[Cl-].CCN(CC)CCCC(C)NC1=C2C=C(OC)C=CC2=NC2=C1C=CC(Cl)=C2
  Pathways:GPCR/G Protein; DNA Damage/DNA Repair; Metabolism; Immunology/Inflammation; Neuroscience
  Receptor:DNA; Histamine N-methyltransferase; PLA2; PLCLP
  Boling pt:
  Melting pt:249-251C
  Solubility:Ethanol: 28 mg/mL (59.21 mM); Water: 53 mg/mL (112.07 mM); DMSO: 14 mg/mL (29.6 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Nuttle LC, et al. Am J Physiol. 1999 Apr;276(4 Pt 2):H1289-94.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting