• Product NameHydroxychloroquine sulfate
• Brief DescriptionInhibitors
• Purification98.92%
• Biological ActivityHydroxychloroquine Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.
• Target NameDNA Alkylation inhibitor; TLR antagonist
• CAS No. 747-36-4
• Calculated MW 433.95
• Formulation C18H26ClN3OH2SO4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:OS(O)(=O)=O.CCN(CCO)CCCC(C)NC1=C2C=CC(Cl)=CC2=NC=C1
  Pathways:DNA Damage/DNA Repair; Immunology/Inflammation
  Receptor:DNA; TLR9
  Boling pt:516.7C
  Melting pt:240C
  Solubility:Water: 67 mg/mL (154.39 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Koranda FC: Antimalarials. J Am Acad Dermatol. 1981 Jun;4(6):650-5.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting