• Product NameFloxuridine
• Brief DescriptionInhibitors
• Purification99.75%
• Biological ActivityFloxuridine (5-fluorodeoxyuridine) is an oncology drug that belongs to the class known as antimetabolites with an GI50 of 5.1 μM for the inhibition of PEPT1.
• Target NameDNA/RNA Synthesis inhibitor
• CAS No. 50-91-9
• Calculated MW 246.19
• Formulation C9H11FN2O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)F)CO)O
  Pathways:DNA Damage/DNA Repair
  Receptor:Thymidylate synthase
  Boling pt:150C
  Melting pt:148C
  Solubility:Ethanol: 10 mg/mL (40.61 mM); Water: 49 mg/mL (199.03 mM); DMSO: 49 mg/mL (199.03 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Ferguson PJ, et al. Br J Pharmacol. 1999 Aug; 127(8):1777-86.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting