• Product NameChloroambucil
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityChlorambucil(WR-139013; CB-1348) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia.
• Target NameDNA Alkylation inhibitor
• CAS No. 305-03-3
• Calculated MW 304.22
• Formulation C14H19Cl2NO2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:OC(=O)CCCC1=CC=C(C=C1)N(CCCl)CCCl
  Pathways:DNA Damage/DNA Repair
  Receptor:DNA Alkylation
  Boling pt:460.1C
  Melting pt:65-70C
  Solubility:Ethanol: 60 mg/mL (197.23 mM); DMSO: 60 mg/mL (197.23 mM)
  Appearance:Off-white Color Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kashiwazaki G, et al. Bioorg Med Chem. 2010 Apr 15;18(8):2887-93.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting