• Product NameGimeracil
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityGimeracil is an inhibitor of dihydropyrimidine dehydrogenase, which inhibits the early step in homologous recombination for double strand breaks repair.
• Target NameAutophagy inhibitor
• CAS No. 103766-25-2
• Calculated MW 145.54
• Formulation C5H4ClNO2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:OC1=CC(=O)NC=C1Cl
  Pathways:Autophagy
  Receptor:DHPS
  Boling pt:281.9C
  Melting pt:274C
  Solubility:DMSO: 29 mg/mL (199.25 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Prescrire Int. 2013 May;22(138):122.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting