• Product NameTrimetazidine dihydrochloride
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityTrimetazidine dihydrochloride is a drug for angina pectoris. Trimetazidine is the first cytoprotective anti-ischemic agent , which improves myocardial glucose utilization through inhibition of fatty acid metabolism.
• Target NameFatty Acid Synthase inhibitor
• CAS No. 13171-25-0
• Calculated MW 339.26
• Formulation C14H22N2O32HCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:Cl.Cl.COC1=C(OC)C(OC)=C(CN2CCNCC2)C=C1
  Pathways:Metabolism
  Receptor:mitochondrial long-chain 3-ketoacyl thiolase
  Boling pt:364C?
  Melting pt:231-235C
  Solubility:Water: 10 mM
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kantor PF, et al. Circ Res. 2000 Mar 17;86(5):580-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting