• Product NameDesipramine hydrochloride
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityA tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
• Target Name5-HT Receptor antagonist; Adrenergic Receptor
• CAS No. 58-28-6
• Calculated MW 302.84
• Formulation C18H23ClN2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:Cl.CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
  Pathways:Neuroscience; GPCR/G Protein
  Receptor:5-HT; Adrenergic Receptor
  Boling pt:407.4C?
  Melting pt:214-216C
  Solubility:Soluble in DMSO
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Zavosh A, et al. Brain Res Bull. 1999 Jul 1;49(4):291-5.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting