• Product NameClevidipine butyrate
• Brief DescriptionInhibitors
• Purification99.86%
• Biological ActivityCleviprex (Clevidipine) is a short-acting dihydropyridine calcium channel antagonist (IC50= 7.1 nM, V(H) = -40 mV ) under development for treatment of perioperative hypertension.
• Target NameAChR antagonist; Calcium Channel inhibitor
• CAS No. 167221-71-8
• Calculated MW 456.32
• Formulation C21H23Cl2NO6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CCCC(=O)OCOC(=O)C1=C(C)NC(C)=C(C1C1=C(Cl)C(Cl)=CC=C1)C(=O)OC
  Pathways:Membrane transporter/Ion channel; Neuroscience
  Receptor:AChR; Calcium Channel
  Boling pt:539.7C
  Melting pt:128-130C
  Solubility:Ethanol: 3 mg/mL (6.57 mM); DMSO: 91 mg/mL (199.42 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Ericsson H, et al. Eur J Pharm Sci. 1999 Apr;8(1):29-37.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting