• Product NameDoxorubicin hydrochloride
• Brief DescriptionInhibitors
• Purification99.37%
• Biological ActivityDoxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
• Target NameTopoisomerase inhibitor
• CAS No. 25316-40-9
• Calculated MW 579.99
• Formulation C27H29NO11HCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
  Pathways:DNA Damage/DNA Repair
  Receptor:Topo II
  Boling pt:810.3C
  Melting pt:216C?
  Solubility:Water: 20 mg/mL (34.48 mM); DMSO: 100 mg/mL warmed (172.41 mM)
  Appearance:Red solid
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Sun W, et al. Y Res, 2009, 69(10), 4294-4300.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting