• Product NameFludarabine
• Brief DescriptionInhibitors
• Purification99.88%
• Biological ActivityFludarabine(NSC 118218), a DNA synthesis inhibitor, is a chemotherapy drug used in the treatment of hematological malignancies.
• Target NameSTAT inhibitor
• CAS No. 21679-14-1
• Calculated MW 285.23
• Formulation C10H12FN5O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C1=NC2=C(N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)N=C(N=C2N)F
  Pathways:JAK/STAT signaling; Stem Cells
  Receptor:STAT1
  Boling pt:747.3C
  Melting pt:265-268C
  Solubility:DMSO: 57 mg/mL (199.83 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Fernndez-Calotti P, et al. Int Immunopharmacol. 2006, 6(5), 715-72

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting