• Product NameKetanserin
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityA selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
• Target Name5-HT Receptor antagonist
• CAS No. 74050-98-9
• Calculated MW 395.43
• Formulation C22H22FN3O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:FC1=CC=C(C=C1)C(=O)C1CCN(CCN2C(=O)NC3=CC=CC=C3C2=O)CC1
  Pathways:GPCR/G Protein; Neuroscience
  Receptor:5-HT2A; 5-HT2C (Human); 5-HT2C (Rat)
  Boling pt:
  Melting pt:227-235C
  Solubility:DMSO: 2 mg/mL (5.05 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Van Nueten JM, et al. J Pharmacol Exp Ther, 1981, 218(1), 217-230.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting