• Product NameAdapalene
• Brief DescriptionInhibitors
• Purification99.53%
• Biological ActivityAdapalene is a topical retinoid primarily used in the treatment of acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions. It is currently marketed by Galderma under the trade names Differin in some countries, and Adaferin in India.
• Target NameRetinoid Receptor agonist
• CAS No. 106685-40-9
• Calculated MW 412.52
• Formulation C28H28O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:COC1=C(C=C(C=C1)C1=CC2=C(C=C1)C=C(C=C2)C(O)=O)C12CC3CC(CC(C3)C1)C2
  Pathways:Metabolism
  Receptor:RAR; RXR
  Boling pt:606.3C?
  Melting pt:319-322C
  Solubility:DMSO: 8 mg/mL (19.39 mM)
  Appearance:White Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Brogden RN, et al. Drugs, 1997, 53(3), 511-519.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting