• Product NameSparfloxacin
• Brief DescriptionInhibitors
• Purification100.00%
• Biological ActivitySparfloxacin is a fluoroquinolone antibiotic used in the treatment of bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription.
• Target NameDNA gyrase inhibitor; Topoisomerase inhibitor
• CAS No. 110871-86-8
• Calculated MW 392.4
• Formulation C19H22F2N4O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:C[C@@H]1CN(C[C@@H](N1)C)C2=C(C3=C(C(=C2F)N)C(=O)C(=CN3C4CC4)C(=O)O)F
  Pathways:DNA Damage/DNA Repair
  Receptor:DNA gyrase; Topo II; Topo IV
  Boling pt:640.4C
  Melting pt:265C
  Solubility:DMSO: 9 mg/mL (22.93 mM)
  Appearance:Yellow Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Schmitz FJ, et al. J Antimicrob ChemOthers. 1998 Apr;41(4):481-4.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting