• Product NameDoxylamine succinate
• Brief DescriptionInhibitors
• Purification99.12%
• Biological ActivityDoxylamine succinate competitively inhibits histamine at H1 receptors with substantial sedative and anticholinergic effects.
• Target NameHistamine Receptor antagonist
• CAS No. 562-10-7
• Calculated MW 388.46
• Formulation C21H28N2O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:OC(=O)CCC(O)=O.CN(C)CCOC(C)(C1=CC=CC=C1)C1=CC=CC=N1
  Pathways:GPCR/G Protein; Immunology/Inflammation; Neuroscience
  Receptor:H1 receptor
  Boling pt:364.9C
  Melting pt:95-98C
  Solubility:Ethanol: 78 mg/mL (200.79 mM); Water: 78 mg/mL (200.79 mM); DMSO: 78 mg/mL (200.79 mM)
  Appearance:White Crystal
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Bookstaff RC, et al. Toxicol Appl Pharmacol, 1996, 141(2), 584-594.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting